lation of a series of enzymes and signaling proteins in affected tissues and cells. Among the proinflammatory enzymes, the inducible forms of nitric oxide synthase (NOS) and cyclooxygenase (COX), which are responsible for increasing the levels of nitric oxide (NO) and prostaglandins (PGE2), are known to be involved in various chronic diseases including multiple sclerosis, Parkinson’s and Alzhei...

9-[[2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine (BIOLF-62) is highly synergistic with either phosphonoformate or phosphonoacetate when used in combination against herpes simplex virus types 1 and 2 in vitro. Acycloguanosine did not show significant synergism with these two compounds. Bromovinyldeoxyuridine and phosphonoformate were highly synergistic against herpes simplex virus type 2, bu...

1 The British Thoracic Society. Intermediate care – hospital-athome in chronic obstructive pulmonary disease. British Thoracic Society guidelines. Thorax 2007; 62: 200–210. 2 British Lung Foundation. Invisible lives – Chronic Obstructive Pulmonary Disease (COPD) – finding the missing millions. www.lunguk.org Date last updated: November 2007. Date last accessed: April 2008. 3 Global Initiative f...

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